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In cell-based studies, CYP51A1 expression in human adrenocortical H295R cells was found to be downregulated by 25-hydroxycholesterol, a feedback inhibitor of cholesterol synthesis

It's the most abundant antioxidant in every human cell and known as the "master antioxidant" for its role in protecting cells from free radicals, as a cofactor in antioxidant enzymes, and regenerating other antioxidants (vitamin C and vitamin E.) (Source 1) In addition to its antioxidant roles, glutathione has many other vital functions, including: Anti-inflammatory actions and immunity Cellular regulation Protein synthesis Liver detoxification Nutrient metabolism Genetic expression Cell signaling And more (Source 1, 2, 3) What are the Benefits of Glutathione Supplements

Plasma levels decline with age