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Es clave en la conjugacin de fase II en el hgado

The presence of ROS causes peroxidation cycles, resulting in the fragmentation of sperm DNA and the oxidation of membrane lipids present in sperm

This ongoing oxidative stress leaves endothelial cells (the lining of blood vessels) highly vulnerable to ongoing damage, contributing to the micro-clotting and "immunothrombosis" frequently observed in Long Haulers

87,88 Subsequent studies suggested that the copper chaperone for superoxide dismutase (CCS) is responsible for chaperoning Cu to MEK1/2, 89 which would be required given the extremely limited bioavailability of Cu I in cells (Section 2.2)