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Evidence From Preclinical & Clinical Studies A) Skin permeation & bioavailability In-vitro penetration: A Franz-cell model showed human skin penetration of GHK-Cu in vitro, supporting the feasibility of topical delivery (PMC)

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A significant finding is its effect in pathological scarring models, such as keloids, where it promoted apoptosis in resistant fibroblasts and reduced cell proliferation during the G0/G1 phase of the cell cycle