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Evidence for a role of endothelin 1 and protein kinase C in nitroglycerin tolerance

ChangJLGongJRizalSPetersonALChangJYaoCet al

This observation is indirectly supported by another study involving kidney transplant recipients, where the carriers of rs55754655 required a higher dose of azathioprine to maintain immunosuppressive effect at 3, 6, and 12 months after transplantation ( The transmembrane transporters have also been shown to regulate the intracellular levels of 6-TGN