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Growth Factor Modulation Beyond the VEGF pathway, BPC-157 research has also investigated potential modulation of other growth factors notably EGF (epidermal growth factor) and FGF (fibroblast growth factor) though this mechanism is considered secondary relative to the angiogenic pathway and the evidence base is less extensive

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However, this introduces unpredictability: the same dose could produce significantly higher plasma levels than intended, and the effect varies by inhibitor potency