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tomentosa are not restricted to the liver, given that one major difference between both transaminases is that while ALT is restricted to the cytosol of hepatocytes, AST may be found in various other tissues, such as myocardium, skeletal muscle, kidneys, brain, pancreas, lungs and blood cells [61]

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Arnaud-Coffin P, Maillet D, and Gan HK, et al (2019) A systematic review of adverse events in randomized trials assessing immune checkpoint inhibitors Int J Cancer 145 (3) 639648 PMID: 30653255 35