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An estimated one-third of patients with chronic HCV infection have cirrhosis attributable to heavy alcohol consumption.[58] In a study in Alaska, investigators compared outcomes in persons who recovered from HCV with those who had chronic HCV and found heavy alcohol use (at least 50 grams of alcohol daily) was associated with the highest incidence of end-stage liver disease, regardless of whether the individual had recovered from HCV or had chronic HCV infection.[59] In addition, separate studies have shown that liver disease progression may continue among persons who heavily use alcohol even if SVR is achieved with HCV treatment

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