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683 Intermittent fasting (IF) has been reported to reduce lipid peroxidation and mitochondrial dysfunction, and one month of IF increased the expression of protective GPX4, partially eliminated the ferroptosis of cortical neurons induced by TBI, and helped to alleviate cognitive impairment

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Even during remission, people with BD show impaired executive and visuospatial cognition, memory, and attention, all of which correlate with increased levels of serum TNF-, IL-1, and IL-6 (65), and 27% of patients with depression had a CRP concentration of more than 3 mg/dl (66)