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Although the magnitude of hydraulic resistance experienced by migrating breast cancer cells in vivo is currently unknown, mathematical modeling indicates that depending on the interstitial fluid viscosity and matrix permeability, the hydraulic resistance within 3D matrices could potentially match or even exceed that observed in microchannels [50, 203]

In fact, it was the successful use of Botox in some people with severe myofascial pain syndrome that led doctors to try it for fibromyalgia

The importance of the SIBLING family of proteins on skeletal mineralisation and bone remodelling

Human trials showed improved cardiovascular outcomes and reduced mortality over 12-year follow-up [4]