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Calcif Tissue Int 2018

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In the presence of elevated oxidative stress, such as in iron overload, sarcoplasmic reticulum Ca 2+ leaks through the Ca 2+ release channels (62), sarcoendoplasmic reticulum Ca 2+ -ATPase activity is inhibited, the sodium-calcium exchanger currents are elevated (63), and L-type calcium channels are reduced (64, 65)

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BellonoNWBayrerJRLeitchDBCastroJZhangCO'DonnellTAet al

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A detailed look at this two-way link is in the stress and immunity article

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