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For instance, NitroSynapsin, tested on patient-derived organoids, was able to normalize neuronal activity, suggesting potential for medications that target neural imbalances even after development

REDEFINE 2 (Type 2 Diabetes) In patients with T2D, CagriSema produced significant weight loss alongside glycemic improvements (HbA1c reduction), outperforming the individual components (Lingvay et al., 2025)