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4) and the relationship between precise patient-specific control of activation level and CAR T cell functionality 20 , we hypothesized that rapamycin may have a greater effect on decreasing the activation of STR compared to LTR CAR T cells

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Several clinical trials have reported promising results in SLE patients through the use of mAbs targeting IFN or IFNAR, resulting in improvements in biomarkers and clinical outcomes (94)

Diesel exhaust particles (DEP) also exert harmful effects and significantly contribute to risk of inhalant allergies in children and adults by exacerbating oxidative stress and the resulting inflammations (124)