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That creates uncertainty in areas such as: long-term use beyond typical protocol durations rare side effects that require large sample sizes to detect interactions with complex medication regimens outcomes in special populations such as pregnancy, cancer history, or severe autoimmune disease The right response to uncertainty is not fear, and it is not blind confidence

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Furthermore, as a common point, rats with severed myotendinous junctions [13] and rats with muscle-to-bone detachment shared in their recovery the same longitudinal collagen fibers orientation (note that the maturation of collagen fibers was seen under Masson trichrome and Sirius red staining)