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As described previously, GSTs are known to clear intracellular ROS and assist in redox balance regulation (38)

SP has been reported to have anti-inflammatory effect (Usman et al., 2020), When B16F10 melanoma cells were treated with 050 m SP, it was found that SP to induce melanin synthesis in a dose-dependent manner by increasing the expression of MITF and tyrosinase via increasing CREB phosphorylation ( In vitro , SP at concentrations of 050 mol/L enhanced melanogenesis in vivo and in vitro by increasing melanin content and Tyr and MITF expression (Heriniaina et al., 2018)