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A growing body of translational research suggests that IN delivery can achieve CNS therapeutic effects while minimizing systemic exposure, allowing patients to experience fewer adverse effects, such as anemia or gastrointestinal upset, which are common concerns with oral or intravenous chelators

Full-B12 Injection may have the following common side effects: Injection site reactions which might include redness, swelling, and pain where the injection was given

Although generally considered safe, Lacarnit Injection might lead to side effects like nausea, vomiting, diarrhea, abdominal pain, and further injection site reactions like swelling, redness, and pain

To assess heterogeneity of the meta-analysis, the Cochran-Q test and I 2 index were utilized