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It is worth noting that the anticancer and immunomodulatory role of bilirubin in nanomedicines was overlooked in some of the above experiments, which focused on its high photothermal conversion efficiency as a photosensitizer on tumors, without noting that the anticancer role of bilirubin/biliverdin as a ROS scavenger in its own right should not be underestimated

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Additionally, onion peel, rich in quercetin and FRS 1,000, has been found to strongly inhibit PDE 5A activity (179)