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Withdrawn from the US market in 2008 for commercial reasons, not safety

Studies have shown that infants delivered by cesarean section, due to bypassing the birth canal, miss out on exposure to beneficial maternal vaginal and intestinal bacteria, leading to delayed and altered early intestinal microbiota colonization compared to vaginally delivered infants ( Staphylococcus and Corynebacterium in their intestines, while the colonization of beneficial bacteria like Bifidobacterium and Lactobacillus is delayed and less abundant (Zhou et al., 2023b)

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