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Thus, at the level of overall glucose homeostasis the AMPK-mediated activation of PDE4B will counter all of the cAMP-PKA-mediated effects in hepatocytes that are stimulated by glucagon as well as those exerted by epinephrine binding to hepatic 2 -adrenergic receptors

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Gamma-glutamyl Peptides and Related Amino Acids in Rat hippocampus In Vitro : Effect of Depolarization and Gamma-Glutamyl Transpeptidase Inhibition