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routine B12 level monitoring is generally unnecessary once replacement is established, as levels do not reliably correlate with tissue stores Important safety considerations: Older adults may have impaired renal function, though this rarely affects B12 therapy given its wide safety margin

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70% faster transit rate), this concentration was applied in subsequent experiments (Supplementary Fig

Data were normalized to the expression of the commonly used reference gene Tbp which encodes TATA-binding protein