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safety, immunological response, and clinical outcome

Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome

While 100 nM MitoQ only minimally increased DPI-induced cell death ( Figure 1C ), higher MitoQ concentrations significantly enhanced DPI-mediated cell toxicity as measured by an increased PI uptake after 24h, in a MYCN-dependent fashion ( Figure 1E )

BOMSS and NHS guidance recommend a daily bariatric-specific multivitamin, intramuscular vitamin B12 (hydroxocobalamin 1 mg every three months), vitamin D, calcium, and iron supplements, with doses tailored to your blood test results by your bariatric team or GP