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5-Alpha Reductase Inhibitors: Drugs like finasteride and dutasteride block the conversion of testosterone to dihydrotestosterone (DHT), a hormone that contributes to prostate growth

Given the FoxO1 ablation induced -cell dedifferentiation and caused hyperglycemia under physiologic stress 22 , we determined whether LOsG/ROS stresses decrease FoxO1 expression and thus induce -cell dedifferentiation

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