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Quantification of phospho-Akt protein revealed that insulin-induced Akt phosphorylation was significantly less in Insr P1195L/ +/ND mice and in WT/HFD mice compared with that in WT/ND mice

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Because methylcobalamin may be advantageous in treating chronically progressive MS as an immunosuppressive medication by enhancing oligodendrocyte maturation and clinical results [35,36,37], this study sought to collect information and review previous research on the function of Cbl in MS and to consider whether it can be applied in the future to treat this disease and its symptoms more effectively

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