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Nature 444 (7119), 624628

When to See a Doctor Prompt medical evaluation is warranted if one or more of the following symptoms occur after the injection treatment: Increased pain or swelling at the injection site that progressively worsens Fever, chills, and/or night sweats Uncontrolled or excessive bleeding at the injection site Persistent numbness or weakness in the neck, shoulder, arm, or upper back Headaches Swelling in the arms Before considering a rotator cuff injection, patients are advised to discuss the risks, benefits, and alternative treatments with their doctor.

8, 9, 10, 11 Oxidative stress occurs as the result of an accumulation of free radicals generated by normal metabolism and various environmental exposures to elicit cellular dysfunction

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