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Growth factors play a major role in initiating the angiogenesis process and several drugs act on these specific growth factors directly or indirectly which can be repurposed to activate angiogenesis and accelerate the healing of different types of wounds (burns, diabetic ulcers, and trauma wounds)

The researchers successfully increased bFGF brain supply via the non-invasive IN route, and hemiparkinsonian rats demonstrated a considerable neuroprotective improvement [127]