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Targeted activation of ferroptosis in colorectal cancer via LGR4 targeting overcomes acquired drug resistance

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Ki values for the binding of the peptides were determined using the Prism 5

R 2 is C 1 -C 6 alkyl, C 1 -C 6 alkyl-OR 6 , C 1 -C 6 alkylC 3 -C 6 cycloalkyl, or C 1 -C 6 alkyl-0O 2 R 6