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[DOI] [PMC free article] [PubMed] [Google Scholar] 129.Strambi M., Longini M., Vezzosi P., Berni S., Buoni S

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Because cuproptosis preferentially targets cells with high oxidative phosphorylation (OXPHOS) dependency, whereas glycolytic tumors remain relatively resistant, it exposes a distinct metabolic vulnerability in cancer and presents unique therapeutic opportunities 165,166