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Tawiah KD, Riley SB, Budelier MM

However: CBT-I is the gold standard non-pharmacological intervention, but: Melatonin and chronotherapy offer partial circadian realignment, but: No current therapy enhances GABAergic neurogenesis , astroglial repair , or neuroimmune modulation vital aspects of long-term sleep restoration

Csar et al

Weight loss accelerates during this window, and the phase 2 clinical trial data published in the New England Journal of Medicine confirms this dramatically