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Vitamin E acetate an additive in ENDS containing cannabis sourced from informal or illicit sources has been linked to e-cigarette or vaping use-associated lung injury (EVALI), with 2,807 incidents leading to hospitalisations or death in the US, highlighting the dangers of unregulated markets

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Certain medical condition s: Dark gums may also be a sign of some medical conditions such as acute necrotizing ulcerative gingivitis (ANUG), Addisons disease, Peutz-Jeghers Syndrome, and oral cancer, for example, malignant melanoma

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