If you dont get enough B12 in your diet or through supplementation, you may develop one or more of the following symptoms [4]: - Mild fatigue during exercise or daily activities - Heart palpitations - Skin paleness or hyperpigmentation - Glossitis (tongue inflammation) - Neurological symptoms such as loss of reflexes, loss of proprioception (knowing where your limbs are without looking at them), forgetfulness Signs that healthcare providers use to detect a B12 deficiency include [4]: - Megaloblastic anemia (abnormally large and nucleated red blood cells) - Abnormal blood work, including decreased levels of haptoglobin
Pang, Z., Lu, Y., Zhou, G., Hui, F., Xu, L., Viau, C., et al
Arandomised controlled trial of a mitochondrial therapeutic target for bipolardepression: mitochondrial agents, N-acetylcysteine, and placebo [publishedcorrection appears in BMC Med
The arginate salt form was engineered to minimize that risk, and from what we've seen, the innovation is significant