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On the other hand, in the final post-operative month periods (Figure 17 and Figure 18), in the BPC 157 rats, the bone tissue of the lesion was minimally active and well organized

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Our data suggest that hypermethylation of the 25-hydroxylases, 1--hydroxylase enzymes, and the vitamin D receptor promoter, accompanied by hypomethylation of CYP24A1, leads to impaired expression and possibly a predisposition to VD deficiency/inadequacy

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