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Prepare for intravenous injection by mixing 1 vial of white lyophilized powder and each of the 3 ampoules with 5ml of sterile water

16,18,19,20,21,22 As cystine influx through the cystineglutamate xCT antiporter occurs concomitantly with glutamate efflux, increased cystine import can also be related to poor prognosis

Blocking DHT Copper peptides can inhibit the enzyme 5-alpha reductase, which is responsible for converting testosterone into DHT, the hormone linked to male and female pattern baldness

Ethics declarations Competing interests MES and DJP were full-time employees of Janssen Pharmaceutica NV during the execution of the study