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A 2016 meta-analysis of nine studies on the effect of carnitine supplementation on weight loss concluded, Study participants who took carnitine supplements lost an average of 1.33 kg more weight than those who took a placebo, regardless of the study duration or L-carnitine dose. In one 9-week study, the carnitine group saw significant improvements in bench press and leg press volumes and reduced blood lactate levels and markers of oxidative stress following training

Sainz RM, Lombo F, Mayo JC

Cell culture studies show stimulation of beta-3 adrenergic receptors in adipocytes, increasing fat oxidation while inhibiting lipogenesis through acetyl CoA carboxylase blockade

is also partially supported by a gift from the Leonard Krieger Fund