Seven days following the intravenous injection of various formulations into healthy mice, major organs (including the heart, liver, spleen, lungs, and kidneys) were harvested and subjected to histopathological examination using H&E staining
This is characterized by an elimination phase, lasting 6 weeks to 6 months, in which grains, legumes, nuts seeds, dairy, eggs, coffee and alcohol are forbidden
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Transcription factor Nrf2 is activated in response to ROS-induced oxidative stress and triggers the expression of its target genes through binding to antioxidant response elements (Ma 2013)