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[16] New Zealand [edit source] The New Zealand Ministry of Health reported in 2005 that: 'The ratio of roll-your-own to manufactured or tailor-made cigarettes consumed by New Zealanders has risen over (at least) the past decade, perhaps reflecting price differences between these products, and currently approaching 50 percent overall.' [17] Taxation [edit source] Consumers' switching to roll-your-own has led to a response among certain tax authorities

Discussion Our findings represent the first characterization of e-cigarette-associated neurovascular alternations in an animal model, and bridge a current knowledge gap between clinical investigation of e-cigarette users and mechanistic studies in cell culture-based systems

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