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Atopic dermatitis, the clinical term for eczema, is a chronic inflammatory skin condition rooted in a dysregulated immune response and a compromised epidermal barrier

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IL-1 is a typical inflammatory mediator produced by nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing 3 (NLRP3) inflammasome, leading to myocardial hypertrophy, heart failure, and coronary atherosclerosis [85, 86]

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