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456 In the spinal cord, the influx of neuropathic signals to the dorsal horn leads to central sensitization, characterized by increased spontaneous neuronal activity, lowered activation thresholds for peripheral stimuli, heightened responses to sub-threshold stimuli, and expansion of receptive fields

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H 2 O 2 is commonly produced as a consequence of the action of superoxide dismutase (SOD), which converts two molecules of superoxide and two protons from the water to H 2 O 2 and molecular oxygen

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