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Glucose-affecting peptides: GH secretagogues can raise blood sugar

In vitro analysis in -MSH-stimulated B16 murine melanoma cells, resveratrol inhibited the cellular melanin production via suppression of melanogenesis-related proteins such as tyrosinase, TRP-1, TRP-2 and microphthalmia-associated transcription factor (MITF) expression 65 without any cytotoxicity up to 200 M

Intracellular iron that exceeds the cells storage capacity leads to the Fenton reaction-induced generation of ROS that can promote cancer-causing mutations, leading to cancer progression or, if ROS levels are high enough, cytotoxicity

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