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doi:10.1002/ptr.6055 Weeks BS

Immunization of mice was carried out by experts from the High Level Technological Service CONICET (STAN No

AMG 133 demonstrated significant dose-dependent weight loss in a phase 1 randomized, double-blind, placebo-controlled clinical trial involving participants with obesity, along with an acceptable safety and tolerability profile [124]

246 These different results suggest that in-depth mechanistic research, such as the study of the effects of oxidative stress on DNMT enzyme activity, transcription, protein stability, and redox modification patterns, will help researchers understand the different biological functions of oxidative stress and develop new treatment strategies