J Pharmacol Exp Ther 187:211217 Ramsay RR, Rashed MS, Nelson SD (1989) In vitro effects of acetaminophen metabolites and analogs on the respiration of mouse liver mitochondria
For example, simultaneously evaluating the expression, enzyme activity, and lipidomic characteristics of GPX4, SLC7A11, ACSL4, LPCAT3, FSP1, and DHODH in the same batch of patient tissues, combined with disease staging and tissue-specific differences between cartilage and synovium, can clarify the dominance of each pathway at different stages
In addition, STAT3 can regulate the membrane expression of a variety of mitochondrial and cell membrane-related genes, thereby affecting mitochondrial function and cell membrane integrity, thereby affecting cell survival and death
Owing to the complexity of ferroptosis and the lack of specific criteria and unique biomarkers of ferroptosis, we were unable to conclude that ferroptosis is involved in the mechanism of EBV reactivation