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The graphical abstract collectively emphasises the coordinated regulation of detoxification pathways, redox metabolism, and physiological responses that contribute to salinity tolerance

Studies have shown that hypoxia and OS during PE pregnancy can stimulate p53 expression, induce trophoblast apoptosis, and inhibit endothelial cell proliferation, leading to cell apoptosis and excessive autophagy at the level of multiple cell dysfunctions [37]

Elevated tNAA and Glx may indicate increased bioenergetics and excitability that may have developed in response to cognitive dysfunction long after injury

A 1 ml syringe may be more comfortable for frequent, smaller doses, while a 3 ml syringe may be better for less frequent, larger doses