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In this case, the underlying problem is ischemia and VEGFs role is to promote angiogenesis and prevent necrosis in ischemic hindlimbs[74]

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As such, a newly recognized form of programmed cell death, which is termed as ferroptosis ( In this study, we found that ferroptosis is responsible for atorvastatin-induced muscular injury both in cardiomyocytes and skeletal muscle cells

Zuo et al., TB-500 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis, Kidney Int., 84(6), 2013