Overexpression of nuclear receptor subfamily 1, group D member 1 (NR1D1)/Rev-Erba, an orphan nuclear receptor, has been shown to enhance the antimycobacterial properties of macrophages and decrease the survival of M.tb by promoting phagosomelysosome maturation through IL-10 repression in human macrophages[53]
Jacamo RO, Mu H, Zhang Q, Chachad D, Wang Z, Ma W, Zhang M, Mak PY, Mak D, Ruvolo P, McQueen T, Lowe S, Zuber J, Eulberg D, Kruschinski A, Konopleva M, Davis RE, Andreeff M
(-)-epicatechin protects hemorrhagic brain via synergistic nrf2 pathways
Selection: The main selection criterion will be the highest score on an abstract submitted for the CUGH annual meeting as judged routinely by the annual meeting Scientific Committee, usually at least three months before the annual meeting, which will allow time to organize sponsored travel