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New England Journal of Medicine, 385(6), 503-515

MAPP investigators performed a 1-year observational cohort study of over 200 women with IC/BPS and identified important clinical factors associated with quality-of-life outcomes and with symptom trajectories over time, including the presence of pain outside the pelvis, the presence of concurrent nonurological chronic pain conditions (such as fibromyalgia and irritable bowel syndrome), and the severity of bladder-focused symptoms (

This pattern shows up during forward flexion, external rotation or even small arcs of movement

Non-approved Substances For the first time, a substance has been included by name as an example in section S0 (Non-approved Substances) of the List