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You should seek medical attention if you have a persistently high resting heart rate, especially with symptoms such as chest pain, fainting, or shortness of breath

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Excessive heat and humidity can accelerate the deterioration of the tobacco, making it dry and harsh

It is characterized by inflammatory cell infiltration and excessive production of proinflammatory cytokines, which contribute to airway remodeling, airflow limitation, and acute exacerbations of the disease (140, 141)