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In aging humans the total body content of iron increases with age (in women after menopause)

While there is ample evidence that B12, as an essential vitamin, has numerous health benefits, there is no evidence that B12 shots have greater benefit than a B12 supplement in pill form

[PubMed: 20333776] (Among 291 patients with acetaminophen overdose seen over a 5 year period, 77% developed gastroinestinal manifestations [nausea, pain, diarrhea] which were associated with higher doses, longer latency and more renal and hepatic complications, but no patient died)

However, it is unclear how EZH2 affects ferroptosis in kidney stones