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The appropriate use of these medications is directed by a rheumatologist

They are naturally produced in the human body and are responsible for a range of functions, such as tissue repair, collagen production, and hormone regulation

Here, we determine structures of cagrilintide bound to Gs-coupled, active, amylin receptors (AMY 1 R, AMY 2 R, AMY 3 R) and calcitonin receptor (CTR) and compare cagrilintide interactions and the dynamics of receptor complexes with previously reported structures of receptors bound to rat amylin, salmon calcitonin or recently developed amylin-based peptides

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