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These analyses, over the extended time frame considered in the current analysis, suggest that cytisinicline may offer a longer-lasting effect in maintaining smoking cessation when compared with varenicline, and potentially indicates that cytisinicline is more effective in reducing the risk of later relapses

Whether decarceration will continue post-Covid is an open questionalthough preliminary data from other countries suggests it will not

Peer review Peer review information Nature Medicine thanks Frederic Sitas and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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