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PE-22-28 raises seizure threshold concerns via TREK-1 blockade Evidence integrity : Dihexa has a retracted key publication

Research shows: 50% degrades within 30 minutes more than 90% by 2 hours When it complexes with copper, everything changes: it becomes enzyme-resistant far more stable capable of transdermal penetration The copper remains biologically silent until it reaches target cells, making the complex both effective and safe

This leads to a brighter complexion, more even skin tone, and a visible reduction in dark spots