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ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma

Primary Handling Editor: Jerome Staal in collaboration with the Nature Medicine team

DMI is known for its electrophilic properties that allow it to modify cysteine residues on proteins, thereby influencing various signaling pathways related to inflammation and oxidative stress [36].mBy reducing oxidative stress, DMI may help restore the balance of redox homeostasis in the brain, which is crucial for maintaining neuronal health and function

Oxidative stress refers to elevated intracellular levels of ROS