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Morusin alleviates aortic valve calcification by inhibiting valve interstitial cell senescence through Ccnd1/Trim25/Nrf2 axis

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10.1002/adma.201502843 150 WuD.ShouX.ZhangY.LiZ.WuG.WuD.et al (2021)

In an alkali-burn rat model with companion HUVEC work, Huang and colleagues reported that BPC-157 upregulated VEGF-A expression in wounded skin and accelerated tube formation in vitro, attributing effects to ERK1/2 signaling a pathway-level overlap but not an exact replication of the VEGFR2-internalization finding (Huang et al., 2015)